Debuffs that can be applied on the player and other party members.
| Icon | Name | Effect | Cure/Prevent | Caused by |
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| Phobia | -50% Evasion Rate, +50% Physical damage received. |
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| Confused | Skip 2 turns. |
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| Fracture | -20% Max Body,
Eventually becomes only -4% Max Body. |
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| Bleeding | -3% Body per turn. |
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| Poisoned | -10% Body per turn. |
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| Toxic | -20% Body per turn. |
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| Infected arm | Death if not treated in time (Approximately 7 location changes. Actual time passed does not affect rate of infection). |
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| Infected leg |
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| Blindness | -75% Hit Rate, the screen will turn black outside of combat if it affects the protagonist. |
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| Critical state | On enemy attack or heal, reduces your Body to 1. |
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| Burning | -10% Body per turn. |
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| Paralyzed | Skip turns indefinitely. |
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| Parasites | Doubles the depletion of Hunger. |
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| Brain Flower | -50% Hit Rate, attacks random allies. |
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| Severe anal bleeding | The character will pause at random intervals in addition to heavy blood loss. |
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| Curse | Affected character will have a countdown starting at 5 which will go down by 1 at the end of each turn, reaching 0 results in instant death. |
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| Soul Sucked | -50% Max Mind,
permanently if The Marriage, Nas'hrah, Baby Demon or Ghoul. |
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| Ruin(I-III) | Rapidly ages the character. Upon reaching stage III character will die from heart attack. |
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| Hunger (I) | Body decreased to a maximum of 90, character damage decreased to 50%. |
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| Hunger (II) | Body decreased to a maximum of 80. |
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| Hunger (III) | Body decreased to a maximum of 70, character damage decreased to 30%. |
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| Hunger (IV) | Body decreased to a maximum of 50, disables the player's legs. |
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| Hunger (V) | Disables the player's eyes, body decreased to a maximum of 30, not eating while inflicted with this de-buff stage will cause death via starvation. |
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| Fear (I-V) | Learn suicide skill (protagonist only), become panophobic, low mind events. |
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